Whole Blood Cells
Cayman Chemical SalIn SodIM CItrate Stock500mL
A covalent inhibitor of K-RasG12C decreases tumor volume in a PaCa-2 pancreatic cancer mouse xenograft model at 1 to 100 mg/kg per day
Cayman Chemical DIhomoLInolenIc ACD ethyl
An ALK5 and ALK4 inhibitor (IC50s 47 and 129 nM respectively) selective for ALK5 and ALK4 over a panel of 27 kinases at 10 UM inhibits ALK7-induced increases in phosphorylated SMAD2 levels in COS-1 cells overexpressing ALK7 at 5 UM inhibits TGF-B-induced but not TNF-a-induced apoptosis in Fao cells at 1 UM decreases IOP and subconjunctival immune cell infiltration in a rabbit model of trabeculectomy at 5 mg/eye
Cayman Chemical SalIn SodIum CItrAT Stock S 1L
A peptide agonist of MC1R induces cAMP accumulation in mouse L-cells expressing human MC1R (EC50 0.5 nM) induces tyrosinase activity in mouse melanoma cells induces long-term skin darkening in frogs at 1.8 mg/kg
Cayman Chemical Linolenic ACD 1g
An a2-AR agonist selectively binds to a2-ARs over a1-ARs (Kis 0.015 and 5 nM respectively) prevents increases in CTnI as well as reduces myocardial apoptosis pyroptosis and ferroptosis in a mouse model of CLP-induced sepsis at 50 UG/kg induces sedation and decreases mechanical nociception in cats at 40 UG/kg
Cayman Chemical LIgnocRIc ACD methyl STR 250mg
An inhibitor of lysosomal acid lipase (IC50 68 nM) selective for LAL over human pancreatic and bovine milk lipoprotein lipases up to a concentration of 10 UM reduces cholesterol accumulation in lysosome-like storage organelles in NPC1-deficient GM03123 cells (0.01-10 UM)
Cayman Chemical HexacosnoIc ACD methyl Ste
An anticonvulsant increases glucose fructose-16-bisphosphate and pyruvate levels in rat brain at 200 mg/kg reduces the severity of audiogenic seizures in a rat model of barbiturate withdrawal-induced convulsions at 400 mg/kg inhibits PTZ- or brainstem stimulation-induced tonic hindlimb extension (ED50s 35 and 70 mg/kg respectively) as well as leptazol-induced clonic seizures (ED50 230 mg/kg) in rats reduces resting tremor by 60 in a macaque model of Parkinsons disease induced by MPTP when administered at a dose of 150 mg/animal
Cayman Chemical xocapum Ct Gnd ofoln 1mg
A ribonucleotide produced by hydrolysis of cytidine 23-cyclic monophosphate via RNase inhibits RNase can be dephosphorylated to cytidine by 3-nucleotidase
Cayman Chemical UnspecIfIed RobIntIn 5mg
An internal standard for the quantification of uracil by GC- or LC-MS
Cayman Chemical 9 E 12 ELInoleIc ACD ethy 50mg
A fluorescent dye has been used for the covalent labeling of oligonucleotides for DNA analysis fluorescence polarization assays and protein FRET experiments ex/em 546/580 nm
Cayman Chemical OctacosnoIc ACD methyl Ste
An anticonvulsant increases glucose fructose-16-bisphosphate and pyruvate levels in rat brain at 200 mg/kg reduces the severity of audiogenic seizures in a rat model of barbiturate withdrawal-induced convulsions at 400 mg/kg inhibits PTZ- or brainstem stimulation-induced tonic hindlimb extension (ED50s 35 and 70 mg/kg respectively) as well as leptazol-induced clonic seizures (ED50 230 mg/kg) in rats reduces resting tremor by 60 in a macaque model of Parkinsons disease induced by MPTP when administered at a dose of 150 mg/animal
Alkali Scientific CellPro Peripheral Blood Separ
The CellProPeripheral Blood Separation Tube is designed for the rapid and efficient isolation of mononuclear cells (MNCs) from peripheral whole blood cord blood or bone marrow using density gradient centrifugation Its built-in separation bracket minimizes sample mixing with the density gradient medium eliminating the need for slow and tedious application of the sample This innovative design ensures that MNCs remain above the separation bracket allowing for easy collection by simply pouring out after centrifugationsaving time and reducing handling steps Manufactured under strict Good Manufacturing Practice (GMP) standards this tube undergoes rigorous third-party testing to ensure it meets the highest cleanliness and performance requirements for laboratory consumables High Efficiency Rapidly isolates peripheral blood mononuclear cells (PBMCs) within 15 minutes Ease of Use MNCs can be collected directly by pouring out after centrifugation eliminating complex extraction steps High Co